褪黑素是人体松果腺分泌的荷尔蒙。由在松果腺的血清素制造。相信松果腺的唯一功能就是制造和分泌褪黑素。
褪黑素补充剂的主要功能是：
* 帮助睡眠。
* 减少时差的影响。
* 作为一种强抗氧化剂。
* 促进大脑维生素B6的磷酸化作用，有利于P5P的形成。
* 促进谷胱甘肽过氧化酶的形成。
几个双盲研究显示，当褪黑素水平低的时候，褪黑素补充剂能有效帮助睡眠。如果一个人褪黑素水平并没有降低，而又服食褪黑素的话，则没有效果。原因是人体一般在睡前分泌褪黑素。黑暗刺激褪黑素分泌，光亮则抑制它分泌。这个过程完全由人体内在的管理荷尔蒙分泌的时钟控制着，叫做 "天然的生理节奏"。低褪黑素水平是引起失眠的最常见原因。
时差感是人体的天然时钟未能在适当时间分泌褪黑素，因此褪黑素补充剂最为管用。
除了帮助睡眠，褪黑素也有助于甲基化过程，这个过程对人体吸收利用维生素B6很重要。因此，现在我们建议，每个服用SuperNu-Thera或Thera Response的人士，在晚上试服褪黑素以确定它是否能有额外的帮助。
对于从谷胱甘肽获益的人士，褪黑素也是重要的，因为它刺激谷胱甘肽过氧化酶的生成。
本品不含：蔗糖，淀粉，大豆，麦，酪蛋白，谷蛋白，奶，谷物，防腐剂，酵素，凝胶，色素或香味。
建议服量： 睡前一小时服一粒，或依医生指引。
成分表： 每剂量（1粒胶囊）含有以下成分：
成分 含量 建议每日服用量
镁(Magnesium Oxide) 100毫克 25%
褪黑素(melatonin) 1毫克 *
* 号表示未建立每日建议服量
其他成分：氧化镁(Magnesium Oxide)，微晶纤维素，硬脂酸镁，褪黑素（melatonin），植物纤维胶囊。
特别提醒：镁补充剂可能引起粪硬度和大便习惯改变。如果这样，请停用并咨询医生。存放于干冷的地方并拧紧瓶盖。远离小孩。
上述陈述没有经过美国食品和药物管理局（FDA）的评估，这些产品也不作为诊断，治疗和治愈疾病或健康状况。
Kirkman's Melatonin Plus Magnesium capsules
are hypoallergenic for individuals with special requirements and
sensitivities. In addition to being a melatonin supplement, each capsule
also contains 100 mg of magnesium for additional benefits. Magnesium can
have a calming effect and may also relax nerve impulses and muscle
contractions.
Melatonin is a hormone secreted in the human body by the pineal gland. It
is manufactured in that gland from serotonin. It is believed that
manufacturing and secreting melatonin is the sole function of the pineal gland.
Melatonin supplementation is used principally for:
• helping people to sleep
• reducing the effects of jet-lag
• as a powerful antioxidant
• stimulating phosphorylation of pyridoxine in the brain to facilitate the formation of
pyridoxal-5-phosphate (P-5-P)
• stimulating glutathione peroxidase formation
Several double-blind studies have shown that melatonin supplementation is
effective in promoting sleep when melatonin levels are low. If an
individual takes melatonin when levels are not reduced, then it has reportedly
no effect. The reason for this is that the body normally secretes melatonin
just before bedtime. Darkness stimulates melatonin secretion, while light
suppresses it. This process is all controlled by an internal body clock
governing hormonal secretions called “natural circadian rhythm.” Low melatonin
levels are considered a very common cause of sleeplessness.
In jet lag, this natural body clock may not allow for secretion of melatonin at
the appropriate time, thereby making melatonin supplementation useful.
In addition to being a sleep aid, melatonin may also help in the methylation
process, which is important in the body’s absorption and utilization of vitamin
B-6. For this reason, we now recommend that everyone who uses Super
Nu-Thera® or Thera Response also try melatonin in the evening to determine if
it provides added benefits.
For those individuals who are deficient in glutathione, melatonin is important
because it stimulates the production of glutathione peroxidase.
Free Of
Sugar, starch, soy, wheat, casein, gluten, milk, corn, preservatives, yeast, gelatin, flavorings, or colorings.
Warnings:
MAGNESIUM SUPPLEMENTS CAN CAUSE CHANGES IN STOOL CONSISTENCY AND BOWEL HABITS. IF THIS OCCURS, DISCONTINUE USE AND DISCUSS THIS MATTER WITH YOUR PHYSICIAN. STORE IN A COOL DRY PLACE AND TIGHTLY CAPPED. KEEP OUT OF THE REACH OF CHILDREN.
These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.